Anti-MBD1 antibodies are used in the immunodetection of the protein methyl-CpG binding domain protein 1. In humans, the canonical protein has a reported length of 605 amino acid residues and a mass of 66.6 kDa. Its subcellular localization is in the nucleus. Up to 11 different isoforms have been reported for this protein. It is widely expressed across many tissue types. MBD1 is reported to be a transcriptional repressor that binds CpG islands in promoters where the DNA is methylated at position 5 of cytosine within CpG dinucleotides. Synonyms for this target antigen include PCM1, RFT, CXXC-type zinc finger protein 3, protein containing methyl-CpG-binding domain 1, the regulator of fibroblast growth factor 2 (FGF-2) transcription, and CXXC3. MBD1 gene orthologs have been reported in the mouse, rat, bovine, frog and chimpanzee species. A number of MBD1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.