Anti-RHBDF1 antibodies are used in the immunodetection of the protein rhomboid 5 homolog 1. In humans, the canonical protein has a reported length of 855 amino acid residues and a mass of 97.4 kDa. Its subcellular localization is in the ER and Golgi. It is reported to be highly expressed in cerebellum, cerebrum, heart, skeletal muscle, placenta, pancreatic islet and testis. A member of the Peptidase S54 protein family, RHBDF1 is reported to regulate ADAM17 protease, a sheddase of the epidermal growth factor (EGF) receptor ligands and TNF, thereby plays a role in sleep, cell survival, proliferation, migration and inflammation. Synonyms for this target antigen include epidermal growth factor receptor, related sequence, epidermal growth factor receptor-related protein, iRhom1, p100hRho, rhomboid family 1, and inactive rhomboid protein 1. RHBDF1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some RHBDF1 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.