Anti-HNRNPL antibodies are used in the immunodetection of the protein heterogeneous nuclear ribonucleoprotein L. In humans, the canonical protein has a reported length of 589 amino acid residues and a mass of 64.1 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. HNRNPL is known to be involved with mRNA processing and the regulation of transcription. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include P/OKcl.14, epididymis secretory sperm binding protein, and HNRPL. HNRNPL gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 140 citations in the literature describe the use of HNRNPL antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.