Anti-CPSF6 antibodies are used in the immunodetection of the protein cleavage and polyadenylation specific factor 6. In humans, the canonical protein has a reported length of 551 amino acid residues and a mass of 59.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the RRM CPSF6/7 protein family, CPSF6 is a known component of the cleavage factor Im (CFIm) complex that functions as an activator of the pre-mRNA 3'-end cleavage and polyadenylation processing required for the maturation of pre-mRNA into functional mRNAs. Synonyms for this target antigen include CFIM68, CFIM72, HPBRII-4, HPBRII-7, cleavage and polyadenylation specificity factor subunit 6, and CFIM. CPSF6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 50 citations in the literature describe the use of CPSF6 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.