Anti-POLR3E antibodies are used in the immunodetection of the protein RNA polymerase III subunit E. In humans, the canonical protein has a reported length of 708 amino acid residues and a mass of 79.9 kDa. Its subcellular localization is in the nucleus. Up to 5 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. POLR3E is known to be involved with innate immune responses. Synonyms for this target antigen include DNA-directed RNA polymerase III 80 kDa polypeptide, RNA polymerase III 80 kDa subunit RPC5, RNA polymerase III subunit C5, and DNA-directed RNA polymerase III subunit RPC5. POLR3E gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. Some POLR3E antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.