Anti-CLCA2 antibodies are used in the immunodetection of the protein chloride channel accessory 2. In humans, the canonical protein has a reported length of 943 amino acid residues and a mass of 103.9 kDa. Its subcellular localization is in the cell membrane and is secreted. It is reported to be expressed in cornea, skin, vagina, esophagus, and larynx. A member of the CLCR protein family, CLCA2 is reported to play a role in modulating chloride current across the plasma membrane in a calcium-dependent manner, and cell adhesion. Post-translational modifications have been described, including N-glycosylation and protein cleavage. Synonyms for this target antigen include CACC3, CLCRG2, CaCC-3, calcium-activated chloride channel regulator 2, and CACC. CLCA2 gene orthologs have been reported in the mouse, bovine and chimpanzee species. A number of CLCA2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.