Anti-RGS13 antibodies are used in the immunodetection of the protein regulator of G protein signaling 13. In humans, the canonical protein has a reported length of 159 amino acid residues and a mass of 19.1 kDa. RGS13 is known to inhibit signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. The RGS13 marker can be used to identify Tissue Resident Mucosal Type Mast Cells and Connective Tissue Type Mast Cells.* Synonyms for this target antigen include regulator of G-protein signalling 13. RGS13 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some RGS13 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4