Anti-PTPRN antibodies are used in the immunodetection of the protein protein tyrosine phosphatase receptor type N. In humans, the canonical protein has a reported length of 979 amino acid residues and a mass of 105.8 kDa. Its subcellular localization is in the cytoplasmic vesicles and cell membrane. Up to 3 different isoforms have been reported for this protein. It is notably expressed in the hypothalamus, hippocampus, cerebral cortex, caudate, and adrenal gland. A member of the Protein-tyrosine phosphatase protein family, PTPRN is reported to play a role in vesicle-mediated secretory processes. Synonyms for this target antigen include IA-2/PTP, IA2, ICA512, R-PTP-N, receptor-type tyrosine-protein phosphatase-like N, ICA 512, PTP IA-2, and IA-2. PTPRN gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of PTPRN antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.