Anti-ECE1 antibodies are used in the immunodetection of the protein endothelin converting enzyme 1. In humans, the canonical protein has a reported length of 770 amino acid residues and a mass of 87.2 kDa. Its subcellular localization is in the cell membrane. Up to 4 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Peptidase M13 protein family, ECE1 is known to be involved with GPCR signaling pathways and cardiac tissue development. The ECE1 gene has been associated with the disease, Hirschsprung disease, cardiac defects, and autonomic dysfunction. Synonyms for this target antigen include ECE. ECE1 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ECE1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.