Anti-CDCA7 antibodies are used in the immunodetection of the protein cell division cycle associated 7. In humans, the canonical protein has a reported length of 371 amino acid residues and a mass of 42.6 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 6 different isoforms have been reported for this protein. It is found to be widely expressed, with higher level in thymus and small intestine. CDCA7 is reported to participate in MYC-mediated cell transformation and apoptosis; induces anchorage-independent growth and clonogenicity in lymphoblastoid cells. Post-translational modifications have been described, including phosphorylation. The CDCA7 gene has been associated with the disease, Immunodeficiency-centromeric instability-facial anomalies syndrome. Synonyms for this target antigen include cell division cycle-associated protein 7 and c-Myc target JPO1. CDCA7 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.