Anti-KLK11 antibodies are used in the immunodetection of the protein kallikrein related peptidase 11. In humans, the canonical protein has a reported length of 282 amino acid residues and a mass of 31.1 kDa. Its subcellular localization is in the Golgi and is secreted. Up to 4 different isoforms have been reported for this protein. It is reported to be expressed in the brain, skin and prostate. A member of the Peptidase S1 protein family, KLK11 is known to be involved with proteolysis. Post-translational modifications have been described, including protein cleavage and glycosylation. The KLK11 marker can be used to identify Respiratory Bronchiole Epithelium Basal Cells.* Synonyms for this target antigen include TLSP, kallikrein-11, hK11, hippostasin, serine protease 20, trypsin-like protease, and PRSS20. KLK11 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4