Anti-GMPPA antibodies are used in the immunodetection of the protein GDP-mannose pyrophosphorylase A. In humans, the canonical protein has a reported length of 420 amino acid residues and a mass of 46.3 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be expressed in fibroblasts. A member of the Transferase hexapeptide repeat protein family, GMPPA is believed to serve as a regulatory subunit and allow allosteric feedback inhibition of GMPPB by GDP-mannose. Synonyms for this target antigen include mannose-1-phosphate guanyltransferase alpha, GMPP-alpha, GTP-mannose-1-phosphate guanylyltransferase alpha, epididymis secretory sperm binding protein, and AAMR. GMPPA gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Some GMPPA antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.