Anti-ADCY2 antibodies are used in the immunodetection of the protein adenylate cyclase 2. In humans, the canonical protein has a reported length of 1091 amino acid residues and a mass of 123.6 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in zona glomerulosa and zona fasciculata in the adrenal gland. A member of the Adenylyl cyclase class-4/guanylyl cyclase protein family, ADCY2 is known to catalyze the formation of the signaling molecule cAMP in response to G-protein signaling. Synonyms for this target antigen include HBAC2, adenylate cyclase type 2, 3',5'-cyclic AMP synthetase, ATP pyrophosphate-lyase 2, adenylate cyclase 2 (brain), and AC2. ADCY2 gene orthologs have been reported in the mouse, rat, bovine, zebrafish, chimpanzee and chicken species. A number of ADCY2 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. In addition, ELISA is also a common application.