Anti-SCNN1B antibodies are used in the immunodetection of the protein sodium channel epithelial 1 subunit beta. In humans, the canonical protein has a reported length of 640 amino acid residues and a mass of 72.7 kDa. Its subcellular localization is in the cytoplasmic vesicles and cell membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the placenta, lung and kidney. A member of the Amiloride-sensitive sodium channel (TC 1.A.6) protein family, SCNN1B is known to be involved with muscle contraction. Post-translational modifications have been described, including N-glycosylation and phosphorylation. Synonyms for this target antigen include ENaCb, ENaCbeta, LIDLS1, PHA1B2, SCNEB, beta-ENaC, beta-NaCH, and BESC1. SCNN1B gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 120 citations in the literature describe the use of SCNN1B antibodies in research. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.