Anti-IFITM3 antibodies are used in the immunodetection of the protein interferon induced transmembrane protein 3. In humans, the canonical protein has a reported length of 133 amino acid residues and a mass of 14.6 kDa. Its subcellular localization is in the cell membrane, lysosomes and cytoplasm. A member of the CD225/Dispanin protein family, IFITM3 is known to be involved with immune response pathways. Post-translational modifications have been described, including ubiquitination, palmitoylation and phosphorylation. The IFITM3 marker can be used to identify CD16 Monocytes.* Synonyms for this target antigen include DSPA2b, IP15, dispanin subfamily A member 2b, interferon-inducible protein 1-8U, and 1-8U. Over 170 citations in the literature describe the use of IFITM3 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4