Anti-IER5 antibodies are used in the immunodetection of the protein immediate early response 5. In humans, the canonical protein has a reported length of 327 amino acid residues and a mass of 33.7 kDa. Its subcellular localization is in the nucleus and cytoplasm. It is reported to be expressed in acute myeloid leukemia (AML) cells. A member of the IER protein family, IER5 is reported to play a role as a transcription factor. Synonyms for this target antigen include SBBI48 and immediate early response gene 5 protein. IER5 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of IER5 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.