Anti-RGS16 antibodies are used in the immunodetection of the protein regulator of G protein signaling 16. In humans, the canonical protein has a reported length of 202 amino acid residues and a mass of 22.7 kDa. Its subcellular localization is in the membrane. It is found to be highly expressed in retina with lower levels of expression in most other tissues. RGS16 is reported to regulate G protein-coupled receptor signaling cascades. Post-translational modifications have been described, including palmitoylation and phosphorylation.
The RGS16 marker can be used to identify Thalamic Excitatory Neurons.* Synonyms for this target antigen include A28-RGS14P, RGS-R, hRGS-r, regulator of G-protein signalling 16, retinal-specific RGS, and A28-RGS14. RGS16 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Some RGS16 antibodies may have been used in research and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4