Anti-BLM antibodies are used in the immunodetection of the protein BLM RecQ like helicase. In humans, the canonical protein has a reported length of 1417 amino acid residues and a mass of 159 kDa. Its subcellular localization is in the nucleus. It is notably widely expressed in many tissue types. A member of the Helicase protein family, BLM is known to be involved with DNA damage pathways and DNA repair. Post-translational modifications have been described, including ubiquitination and phosphorylation. The BLM gene has been associated with the disease, Bloom syndrome. Synonyms for this target antigen include MGRISCE1, RECQ2, RECQL2, RECQL3, recQ-like DNA helicase BLM, and BS. BLM gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.