Anti-ADAM12 antibodies are used in the immunodetection of the protein ADAM metallopeptidase domain 12. In humans, the canonical protein has a reported length of 909 amino acid residues and a mass of 99.5 kDa. Its subcellular localization is in the cell membrane and is secreted. Up to 4 different isoforms have been reported for this protein. It is notably expressed in the placenta and testis. ADAM12 is known to be involved in skeletal muscle regeneration, specifically at the onset of cell fusion. Post-translational modifications have been described, including protein cleavage and glycosylation. Synonyms for this target antigen include CAR10, MCMP, MCMPMltna, MLTN, MLTNA, and ADAM12-OT1. ADAM12 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.