Anti-VTN antibodies are used in the immunodetection of the protein vitronectin. In humans, the canonical protein has a reported length of 478 amino acid residues and a mass of 54.3 kDa. It has been described to be a secreted protein. It is reported to be expressed in the retina pigment epithelium. VTN is known to be involved with cell adhesion and cell migration. Post-translational modifications have been described, including O-glycosylation, sulfation and phosphorylation. Synonyms for this target antigen include VN, VNT, complement S-protein, epibolin, serum spreading factor, somatomedin B, and V75. VTN gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. Over 70 citations in the literature describe the use of VTN antibodies in research. ELISA, Western Blot, and Immunohistochemistry are common applications for these antibodies.