Anti-RGS6 antibodies are used in the immunodetection of the protein regulator of G protein signaling 6. In humans, the canonical protein has a reported length of 472 amino acid residues and a mass of 54.4 kDa. Its subcellular localization is in the cell membrane, nucleus, and cytoplasm. Up to 15 different isoforms have been reported for this protein. RGS6 is reported to regulate G protein-coupled receptor signaling cascades. The RGS6 marker can be used to identify Vascular Smooth Muscle Cells.* Synonyms for this target antigen include HA117, S914, regulator of G-protein signalling 6, and GAP. RGS6 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species. A number of RGS6 antibodies have been mentioned in research publications and have associated citations. Western Blot, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are common applications for these antibodies.
*HuBMAP Human Reference Atlas v1.4