Anti-TSKS antibodies are used in the immunodetection of the protein testis specific serine kinase substrate. In humans, the canonical protein has a reported length of 592 amino acid residues and a mass of 65.1 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is reported to be highly expressed in the testis. TSKS is believed to play a role in testicular physiology, most probably in the process of spermatogenesis or spermatid development. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include protein phosphatase 1, regulatory subunit 161, testis specific serine/threonine kinase substrate, testis-specific kinase substrate, and STK22 substrate 1. TSKS gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Western Blot is the most common application for the TSKS antibodies listed below. Immunofluorescence and Immunohistochemistry are also common applications.