Anti-TRPM1 antibodies are used in the immunodetection of the protein transient receptor potential cation channel subfamily M member 1. In humans, the canonical protein has a reported length of 1603 amino acid residues and a mass of 182.2 kDa. Its subcellular localization is in the ER and cell membrane. Up to 7 different isoforms have been reported for this protein. It is reported to be expressed in the retina where it localizes to the outer plexiform layer. It is a member of the Transient receptor (TC 1.A.4) protein family. Post-translational modifications have been described, including glycosylation. The TRPM1 marker can be used to identify Retinal Bipolar Neuron.* Synonyms for this target antigen include LTRPC1, MLSN1, long transient receptor potential channel 1, melastatin-1, transient receptor potential melastatin family, and CSNB1C. TRPM1 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4