PMSL2 is an alias for the gene, PMS1 homolog 2, mismatch repair system component, in humans. Other names include: Mismatch repair endonuclease PMS2; DNA mismatch repair protein PMS2; PMS1 protein homolog 2; Mismatch repair endonuclease PMS2 ; HNPCC4; PMS2 postmeiotic segregation increased 2 (S. cerevisiae). The encoded protein is an enzyme with an amino acid length of 862 and a mass of 95.8 kDa. Other isoforms may exist. PMSL2 is a member of the DNA mismatch repair MutL/HexB family. This gene shares homology with other species, including: Mouse.