Anti-TLR6 antibodies are used in the immunodetection of the protein toll like receptor 6. In humans, the canonical protein has a reported length of 796 amino acid residues and a mass of 91.9 kDa. Its subcellular localization is in the cytoplasmic vesicles, Golgi, and cell membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in monocytes, CD11c+ immature dendritic cells, plasmacytoid pre-dendritic cells and dermal microvessel endothelial cells. A member of the Toll-like receptor protein family, TLR6 is known to participate in the innate immune response to Gram-positive bacteria and fungi. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include CD286. TLR6 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species. Over 90 citations in the literature describe the use of TLR6 antibodies in research. ELISA, Flow Cytometry, Western Blot, and Immunohistochemistry are common applications for these antibodies.