Anti-AMICA1 antibodies are used in antigen-specific immunodetection in biological samples. The target AMICA1 is a known alias name of the protein junction adhesion molecule like, encoded by the JAML gene in humans. This 394-amino acid residue protein is reported to be a transmembrane protein of the plasma membrane of leukocytes that control their migration and activation through interaction with CXADR, a plasma membrane receptor found on adjacent epithelial and endothelial cells. It is localized to the cell membrane of the cell and features glycosylated post-translational modifications. It is reported to be expressed in many tissues, such as the cerebral cortex, testis, and bronchus.