Anti-CALCB antibodies are used in the immunodetection of the protein calcitonin related polypeptide beta. In humans, the canonical protein has a reported length of 127 amino acid residues and a mass of 13.7 kDa. It has been described to be a secreted protein. A member of the Calcitonin protein family, CALCB is known to be involved with GPCR signaling pathways and the regulation of intracellular calcium. The CALCB marker can be used to identify Dorsal Excitatory Neurons.* Synonyms for this target antigen include CGRP-II, CGRP2, calcitonin gene-related peptide 2, beta-CGRP, beta-type CGRP, and CALC2. CALCB gene orthologs have been reported in the rat, bovine, frog, chimpanzee and chicken species. Over 70 citations in the literature describe the use of CALCB antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.
*HuBMAP Human Reference Atlas v1.4