Anti-Importin 8 antibodies are used for the immunodetection of the protein encoded by the IPO8 gene. In humans, the canonical protein has a reported length of 1037 amino acid residues and a mass of 119.9 kDa. Its subcellular localization is in the nucleus and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the Importin beta protein family, it is known to be involved in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. The gene encoding this protein is implicated in VISS syndrome. Other names for this target antigen include VISS, RAN binding protein 8, imp8, ran-binding protein 8, and RANBP8. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Some Importin 8 antibodies may have been used in research and have associated citations. Immunohistochemistry is a widely used application for these antibodies. Western Blot and Immunofluorescence are also common applications.