Anti-TACR3 antibodies are used in the immunodetection of the protein tachykinin receptor 3. In humans, the canonical protein has a reported length of 465 amino acid residues and a mass of 52.2 kDa. Its subcellular localization is in the cell membrane. A member of the G-protein coupled receptor 1 protein family, TACR3 is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). Post-translational modifications have been described, including palmitoylation and glycosylation. The TACR3 marker can be used to identify Deep-Layer Near-Projecting Neurons, Amygdala Excitatory Neurons, and Medulla Oblongata Splatter Neurons.* Synonyms for this target antigen include NK-3R, NK3, NK3R, NKR, TAC3R, TAC3RL, neuromedin-K receptor, and HH11. TACR3 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.
*HuBMAP Human Reference Atlas v1.4