Anti-ARL6 antibodies are used in the immunodetection of the protein ADP ribosylation factor like GTPase 6. In humans, the canonical protein has a reported length of 186 amino acid residues and a mass of 21.1 kDa. Its subcellular localization is in the membrane, cell projections, and cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably widely expressed in many tissue types. A member of the Arf protein family, ARL6 is known to be involved in membrane protein trafficking at the base of the ciliary organelle. The ARL6 gene has been associated with the disease, Bardet-Biedl syndrome. Synonyms for this target antigen include ADP-ribosylation factor-like protein 6 and Bardet-Biedl syndrome 3 protein. ARL6 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of ARL6 antibodies have been mentioned in research publications and have associated citations. Immunohistochemistry is a widely used application for these antibodies. ELISA and Western Blot are also common applications.