Anti-NSP antibodies enable researchers to detect and measure the NSP antigen in biological samples. This target is a reported synonym of the RTN1 gene, which encodes reticulon 1. This protein is known to function in brain development and the regulation of cell differentiation, among other biological roles. The human version of NSP has a canonical amino acid length of 776 residues and a protein mass of 83.6 kilodaltons, although 3 isoforms have been identified. It is reported to be localized in the ER and Golgi of cells and notably expressed in the pancreas, cerebral cortex, and cerebellum.