Anti-SDC4 antibodies are used in the immunodetection of the protein syndecan 4. In humans, the canonical protein has a reported length of 198 amino acid residues and a mass of 21.6 kDa. It has been described to be a secreted protein. Up to 2 different isoforms have been reported for this protein. It is notably expressed in fibroblasts. A member of the Syndecan proteoglycan protein family, SDC4 is known to be involved with cell migration. Post-translational modifications have been described, including O-glycosylation. Synonyms for this target antigen include amphiglycan, ryudocan amphiglycan, ryudocan core protein, syndecan 4 (amphiglycan, ryudocan), syndecan proteoglycan 4, and SYND4. SDC4 gene orthologs have been reported in the mouse, rat, bovine, chimpanzee and chicken species. Over 80 citations in the literature describe the use of Sdc4 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA, Immunofluorescence, and Immunohistochemistry are also common applications.