Anti-RPS6KA2 antibodies are used in the immunodetection of the protein ribosomal protein S6 kinase A2. In humans, the canonical protein has a reported length of 733 amino acid residues and a mass of 83.2 kDa. Its subcellular localization is in the nucleus and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be widely expressed with higher expression in the lung, skeletal muscle, brain, uterus, ovary, thyroid and prostate. A member of the AGC Ser/Thr protein kinase protein family, RPS6KA2 is a type of serine/threonine-protein kinase that acts downstream of ERK (MAPK1/ERK2 and MAPK3/ERK1) signaling and mediates mitogenic and stress-induced activation of transcription factors, regulates translation, and mediates cellular proliferation, survival, and differentiation. Synonyms for this target antigen include MAPKAPK1C, RSK, RSK3, S6K-alpha, S6K-alpha2, p90-RSK3, p90RSK2, and HU-2. Over 380 citations in the literature describe the use of RPS6KA2 antibodies in research. Western Blot is a widely used application for these antibodies. In addition, Immunohistochemistry is also a common application.