Anti-LILRA4 antibodies are used in the immunodetection of the protein leukocyte immunoglobulin like receptor A4. In humans, the canonical protein has a reported length of 499 amino acid residues and a mass of 55.2 kDa. Its subcellular localization is in the cell membrane. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the testis, spleen, and lymph node. LILRA4 is reported to function coreceptor to limit the innate immune responses to viral infections; signaling occurs via FCER1G. Post-translational modifications have been described, including glycosylation. The LILRA4 marker can be used to identify Thymic Plasmacytoid Dendritic Cells.* Synonyms for this target antigen include ILT7, leukocyte immunoglobulin-like receptor subfamily A member 4, CD85 antigen-like family member G, and CD85g. LILRA4 gene orthologs have been reported in the mouse, rat and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4