Anti-KIR2DS1 antibodies are used in the immunodetection of the protein killer cell immunoglobulin like receptor, two Ig domains and short cytoplasmic tail 1. In humans, the canonical protein has a reported length of 304 amino acid residues and a mass of 33.6 kDa. Its subcellular localization is in the cell membrane. It is noted to be expressed by NK cells. A member of the Immunoglobulin protein superfamily, KIR2DS1 is a known receptor on natural killer (NK) cells for some HLA-C alleles such as w6. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include CD158a, killer cell immunoglobulin-like receptor 2DS1, CD158 antigen-like family member H, and CD158H. Over 130 citations in the literature describe the use of KIR2DS1 antibodies in research. Flow Cytometry is a widely used application for these antibodies. In addition, ELISA is also a common application.