Anti-ILK antibodies are used in the immunodetection of the protein integrin linked kinase. In humans, the canonical protein has a reported length of 452 amino acid residues and a mass of 51.4 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Up to 3 different isoforms have been reported for this protein. It is reported to be highly expressed in the heart followed by skeletal muscle, pancreas and kidney. A member of the TKL Ser/Thr protein kinase protein family, ILK is a known receptor-proximal protein kinase regulating integrin-mediated signal transduction. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include ILK-1, ILK-2, P59, p59ILK, integrin-linked protein kinase, and HEL-S-28. ILK gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.