Anti-FCER2 antibodies are used in the immunodetection of the protein Fc epsilon receptor II. In humans, the canonical protein has a reported length of 321 amino acid residues and a mass of 36.5 kDa. Its subcellular localization is in the cell membrane and is secreted. It is notably expressed in the tonsil, spleen, lymph node, bone marrow, and appendix. FCER2 is known to be involved with immune response pathways. Post-translational modifications have been described, including O-glycosylation. The FCER2 marker can be used to identify Naive B Cells, Follicular Dendritic Cells, and Transitional Immature B Cells.* Synonyms for this target antigen include CD23, CD23A, CLEC4J, FCE2, FCErII, IGEBF, low affinity immunoglobulin epsilon Fc receptor, and BLAST-2. FCER2 gene orthologs have been reported in the mouse, rat, bovine and chimpanzee species.
*HuBMAP Human Reference Atlas v1.4