Anti-ARHGEF7 antibodies are used in the immunodetection of the protein Rho guanine nucleotide exchange factor 7. In humans, the canonical protein has a reported length of 803 amino acid residues and a mass of 90 kDa. Its subcellular localization is in the cell junctions and cytoplasm. Alternative splicing is reported to yield 6 different isoforms for this protein. ARHGEF7 is known to act as a RAC1 guanine nucleotide exchange factor (GEF) and can induce membrane ruffling. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include COOL-1, COOL1, Nbla10314, P50, P50BP, P85, P85COOL1, and BETA-PIX.