Anti-FRS2 antibodies are used in the immunodetection of the protein fibroblast growth factor receptor substrate 2. In humans, the canonical protein has a reported length of 508 amino acid residues and a mass of 57 kDa. Its subcellular localization is in the membrane. It is reported to be highly expressed in the heart, brain, spleen, lung, liver, skeletal muscle, kidney and testis. FRS2 is a reported adaptor protein that links activated FGR and NGF receptors to downstream signaling pathways. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include FRS2A, FRS2alpha, SNT, SNT-1, SNT1, FGFR signalling adaptor, FGFR substrate 2, and FRS1A. FRS2 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. Over 170 citations in the literature describe the use of FRS2 antibodies in research. Western Blot is a widely used application for these antibodies. ELISA and Immunohistochemistry are also common applications.