Anti-SH2B3 antibodies are used in the immunodetection of the protein SH2B adaptor protein 3. In humans, the canonical protein has a reported length of 575 amino acid residues and a mass of 63.2 kDa. It is notably widely expressed in many tissue types. A member of the SH2B adapter protein family, SH2B3 is known to be involved with hematopoietic stem cell differentiation and intracellular signal transduction. The SH2B3 gene has been associated with the disease, Celiac disease. Synonyms for this target antigen include LNK, SH2B adapter protein 3, lymphocyte-specific adapter protein Lnk, signal transduction protein Lnk, and IDDM20. SH2B3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species. A number of SH2B3 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Flow Cytometry, Immunocytochemistry, Immunofluorescence, and Immunohistochemistry are also common applications.