Anti-Lactotransferrin antibodies are used for the immunodetection of the protein encoded by the LTF gene. In humans, the canonical protein has a reported length of 710 amino acid residues and a mass of 78.2 kDa. Its subcellular localization is in the cytoplasm and is secreted. A member of the Transferrin protein family, it is known to be involved with innate immune responses. Post-translational modifications have been described, including phosphorylation and glycosylation.
The lactotransferrin marker can be used to characterize Myelocytes, Bronchus Submucosal Gland Myoepithelial Cells Serous Secreting Cells, Bronchus Serous Cells, and Trachea Serous Cells.* Other names for this target antigen include HEL110, HLF2, LF, epididymis luminal protein 110, growth-inhibiting protein 12, kaliocin-1, lactoferricin, and GIG12. Gene orthologs have been identified in the mouse, rat, bovine and chimpanzee species. Over 110 citations in the literature describe the use of Lactotransferrin antibodies in research. ELISA is a widely used application for these antibodies. Western Blot and Immunohistochemistry are also common applications.
*HuBMAP Human Reference Atlas v1.4