Anti-TLE1 antibodies are used in the immunodetection of the protein TLE family member 1, transcriptional corepressor. In humans, the canonical protein has a reported length of 770 amino acid residues and a mass of 83.2 kDa. Its subcellular localization is in the nucleus. It is notably widely expressed in many tissue types. A member of the WD repeat Groucho/TLE protein family, TLE1 is reported to be a transcriptional corepressor that binds to a number of transcription factors. Post-translational modifications have been described, including ubiquitination and phosphorylation. Synonyms for this target antigen include ESG1, GRG1, transducin-like enhancer protein 1, enhancer of split groucho-like protein 1, transducin like enhancer of split 1, and ESG. TLE1 gene orthologs have been reported in the mouse, rat, frog, chimpanzee and chicken species. A number of TLE1 antibodies have been mentioned in research publications and have associated citations. Western Blot is a widely used application for these antibodies. Immunofluorescence and Immunohistochemistry are also common applications.