Anti-DNAI3 antibodies are used in the immunodetection of the protein dynein axonemal intermediate chain 3. In humans, the canonical protein has a reported length of 891 amino acid residues and a mass of 102.9 kDa. Its subcellular localization is in the cytoplasm. Up to 2 different isoforms have been reported for this protein. It is notably expressed in the fallopian tube and testis. DNAI3 is known to act as a negative regulator of cell migration, invasion, and metastasis downstream of p53/TP53, through inhibition of Arp2/3 complex-mediated actin polymerization. Synonyms for this target antigen include WD repeat-containing protein 63, dynein intermediate chain 3, axonemal, testicular tissue protein Li 225, testis development protein NYD-SP29 (NYD-SP29), and WD repeat domain 63. DNAI3 gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.