Anti-proton activated chloride channel 1 antibodies are used for the immunodetection of the protein encoded by the PACC1 gene. In humans, the canonical protein has a reported length of 350 amino acid residues and a mass of 40 kDa. Its subcellular localization is in the cell membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. It is found to be widely expressed, with highest expression in the brain. It is a member of the Proton-activated chloride channel protein family. Post-translational modifications have been described, including N-glycosylation. Other names for this target antigen include C1orf75, PAC, PAORAC, TMEM206, hPAC, hTMEM206, proton-activated chloride channel, and ASOR. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.