Anti-CRACD antibodies are used in the immunodetection of the protein capping protein inhibiting regulator of actin dynamics. In humans, the canonical protein has a reported length of 1233 amino acid residues and a mass of 136.8 kDa. Its subcellular localization is in the cytoplasm. It is reported to be expressed in intestinal epithelial cells. CRACD is known to be involved in epithelial cell integrity by acting on the maintenance of the actin cytoskeleton. Synonyms for this target antigen include cancer-related regulator of actin dynamics. CRACD gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.