Anti-MACIR antibodies are used in the immunodetection of the protein macrophage immunometabolism regulator. In humans, the canonical protein has a reported length of 206 amino acid residues and a mass of 23.1 kDa. Its subcellular localization is in the cytoplasm. A member of the UNC119-binding protein family, macir is reported to regulate the macrophage function, by enhancing the resolution of inflammation and wound repair functions mediated by M2 macrophages. Post-translational modifications have been described, including phosphorylation. Synonyms for this target antigen include UNC119-binding protein C5orf30 and UPF0684 protein C5orf30. MACIR gene orthologs have been reported in the mouse, rat, bovine, frog, zebrafish, chimpanzee and chicken species.