Anti-syntaxin binding protein 5L antibodies are used for the immunodetection of the protein encoded by the STXBP5L gene. In humans, the canonical protein has a reported length of 1186 amino acid residues and a mass of 131.9 kDa. Its subcellular localization is in the cell membrane and cytoplasm. Alternative splicing is reported to yield 2 different isoforms for this protein. It is notably expressed in the kidney, hippocampus and lung carcinoma. A member of the WD repeat L(2)GL protein family, it is reported to play a role in vesicle trafficking and exocytosis inhibition. Post-translational modifications have been described, including ubiquitination and phosphorylation. Other names for this target antigen include syntaxin-binding protein 5-like, lethal(2) giant larvae protein homolog 4, syntaxin binding protein 5 like, tomosyn-2, tomosyn-like, and LLGL4. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.