Anti-FCH and mu domain containing endocytic adaptor 1 antibodies are used for the immunodetection of the protein encoded by the FCHO1 gene. In humans, the canonical protein has a reported length of 889 amino acid residues and a mass of 96.9 kDa. Its subcellular localization is in the membrane. Alternative splicing is reported to yield 3 different isoforms for this protein. It is reported to be highly expressed in the lymphoid cells. A member of the FCHO protein family, it is reported to function in an early step of clathrin-mediated endocytosis. The gene encoding this protein is implicated in Immunodeficiency. Other names for this target antigen include F-BAR domain only protein 1, FCH domain only 1, FCH domain only protein 1, and IMD76. Gene orthologs have been identified in the mouse, rat, bovine, frog, chimpanzee and chicken species.