Anti-PGAP6 antibodies are used in the immunodetection of the protein post-GPI attachment to proteins 6. In humans, the canonical protein has a reported length of 771 amino acid residues and a mass of 84.8 kDa. Its subcellular localization is in the lysosomes and cell membrane. It is reported to be expressed in the pancreas, placenta, spleen, liver, kidney, bone marrow, peripheral blood leukocytes and tonsil. A member of the TMEM8 protein family, PGAP6 is reported to be involved in lipid remodeling steps of GPI-anchor maturation. Post-translational modifications have been described, including glycosylation. Synonyms for this target antigen include GPI processing phospholipase A2, five-span transmembrane protein M83, post-glycosylphosphatidylinositol attachment to proteins 6, transmembrane protein 6, and post-GPI attachment to proteins factor 6. PGAP6 gene orthologs have been reported in the mouse, rat, bovine, frog, chimpanzee and chicken species.