Anti-VPS52 subunit of GARP complex antibodies are used for the immunodetection of the protein encoded by the VPS52 gene. In humans, the canonical protein has a reported length of 723 amino acid residues and a mass of 82.2 kDa. Its subcellular localization is in the Golgi and membrane. Alternative splicing is reported to yield 2 different isoforms for this protein. A member of the VPS52 protein family, it is known to act as component of the GARP complex that is involved in retrograde transport from early and late endosomes to the trans-Golgi network (TGN). Other names for this target antigen include SAC2, SACM2L, dJ1033B10.5, vacuolar protein sorting-associated protein 52 homolog, SAC2 suppressor of actin mutations 2-like protein, and ARE1. Gene orthologs have been identified in the mouse, rat, bovine, frog, zebrafish and chimpanzee species.